Eosinophil count, serum CCL17/18/26 and immunoglobulin E levels in atopic dermatitis: upadacitinib phase 2 study analysis
نویسندگان
چکیده
منابع مشابه
prebiotic supplementation modulates serum immunoglobulin e levels and improves total scoring atopic dermatitis score in children with atopic dermatitis: a randomized double blind controlled trial
b ac k gro und : atopic dermatitis (ad) is a prevalent chronic disease in children aging from 6 months to 12 years old. recent studies have shown a positive effect of prebiotics in the prevention and treatment of ad. the mechanism of this effect has not been clearly established. the objective of this study was to investigate the effect of supplementation of prebiotic on serum immunoglobulin e (...
متن کاملRelationship between atopic dermatitis and immunoglobulin E.
Coca and Grove (1925) concluded that serum factors, which they called reagins, were present in individuals with allergic respiratory disease. More than 40 years later, reaginic antibody was shown by Johansson and Ichizaka to belong to the immunoglobin E (IgE) class of immunoglobins. It has been established that the Fc component of IgE has an affinity for surface receptors on mast cells and baso...
متن کاملAssociation of LL-37 and IL-31 serum levels with SCORing Atopic Dermatitis (SCORAD) score in atopic dermatitis patients
Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic dermatitis. Myriad pieces of evidence have pointed to the major roles of LL-37 and interleukin-31 (IL31)in atopic dermatitis. The studies on atopic dermatitis are still limited i...
متن کاملEffect of processed foods on serum levels of eosinophil cationic protein among children with atopic dermatitis
The prevalence of atopic dermatitis (AD) in school-age children has increased in industrialized countries. As diet is one of the main factors provoking AD, some studies have suggested that food additives in processed foods could function as pseudoallergens, which comprise the non-immunoglobulin E-mediated reaction. Eosinophil cationic protein (ECP) is an eosinophil granule protein released duri...
متن کاملVitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study
BACKGROUND Low circulating vitamin D levels have been associated with risk of asthma, atopic dermatitis, and elevated total immunoglobulin E (IgE). These epidemiological associations, if true, would have public health importance, since vitamin D insufficiency is common and correctable. METHODS AND FINDINGS We aimed to test whether genetically lowered vitamin D levels were associated with risk...
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ژورنال
عنوان ژورنال: World Allergy Organization Journal
سال: 2020
ISSN: 1939-4551
DOI: 10.1016/j.waojou.2020.100429